Studies on synthesis and bioactivity of 2-alkenyl-4 (1H) -quinolone
Tang, Y.; Wu, K.; Feng, X.; Huang, L.
Yao Xue Xue Bao 33(4): 269-274
1998
ISSN/ISBN: 0513-4870 PMID: 11939066 Document Number: 490928
Three 2-alkenyl-4(1H)-quinolone compounds(I-III) were synthesized by two methods. III is a new compound from Evodia rutaecarpa and was synthesized through the reaction of the aldehyde intermediate(5) with Wittig reagent. The other two compounds were synthesized for the first time. These compounds showed vasodilating and antibacteria effects in pharmacological tests.
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