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Intracellular solubility of hybrid growth hormones

Levichkin, I.V.; Arsen'eva, D.A.; Shul'ga, A.A.

Molekuliarnaia Biologiia 32(2): 317-322

1998

ISSN/ISBN: 0026-8984
PMID: 9608949
Document Number: 490091
The effects of homologous exchanges of extended regions in human growth hormone molecule were studied as were the effects of cultivation temperature and inducer concentration on the formation of inclusion bodies during bacterial synthesis. Hybrid hormones were obtained. Compared to human growth hormone, they had increased solubility in vivo. A conclusion regarding the possible participation of functional epitopes in intracellular protein aggregation during their production in heterologous systems.

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Linquette, M. 1970: Cyclic A.M.P., messenger of the intracellular activity of some hormones Lille Medical: Journal de la Faculte de Medecine et de Pharmacie de l'Universite de Lille 15(9): 1290-1294
Fahr, F.; Kala, H.; Diallo, B.; Metzner, J. 1985: The enhancement of solubility of problem drugs. 5. Solubility of griseofulvin-methylcellulose-PEG coprecipitates Die Pharmazie 40(5): 362-363
Nakane, P.K. 1971: Application of peroxidase-labelled antibodies to the intracellular localization of hormones Acta Endocrinologica. Supplementum 153: 190-204
Janssen, J.A.M.J.L.; Visser, W.E.; van der Lely, A.J. 2004: Still no indications that the treatment of growth hormone deficient adults with growth hormones is unsafe Nederlands Tijdschrift Voor Geneeskunde 148(30): 1486-1489
Tang, T.; Kiang, J.G.; Cox, B.M. 1994: Opioids acting through delta receptors elicit a transient increase in the intracellular free calcium concentration in dorsal root ganglion-neuroblastoma hybrid ND8-47 cells Journal of Pharmacology and Experimental Therapeutics 270(1): 40-46
Kovár, J. 1986: Hybridoma cultivation in defined serum-free media: growth-supporting substances. II. Insulin, other hormones, and growth factors Folia Biologica 32(5): 304-310
Zatko, T.; Matejovicova, B.; Boledovicova, M.; Vondrakova, M.; Bezakova, A.; Sirotkin, A.V. 2013: Growth and obesity and its association with plasma level of steroid hormones and insulin-like growth factor-I (IGF-I) in Slovak female students Bratislavske Lekarske Listy 114(10): 573-580
Lian, J.B.; Stein, G.S. 1993: The developmental stages of osteoblast growth and differentiation exhibit selective responses of genes to growth factors (TGF beta 1) and hormones (vitamin D and glucocorticoids) Journal of Oral Implantology 19(2): 95
Kennedy, J.C.; Ekpaha-Mensah, J.A. 1973: Histoincompatibility recognition reaction by irradiated or mitomycin-treated parental cells against hybrid spleen cells produces hybrid cell proliferation and illusion of reaction of hybrid against parent Journal of Immunology 111(6): 1639-1652
Kim, H.; Rhu, D.; Hwang, H.; Choi, E. 2003: Performance of a hybrid SBR with fixed bed and suspended growth Water Science and Technology: a Journal of the International Association on Water Pollution Research 48(11-12): 309-317
Marastoni, M.; Salvadori, S.; Balboni, G.; Borea, P.A.; Tomatis, R. 1989: Synthesis and activity of dermorphin-growth hormone releasing factor hybrid peptides Arzneimittel-Forschung 39(6): 639-641
Tarasov, A.P.; Sviridov, V.V. 1986: Capacity of the polynucleotide phosphorylase-releasing factor to stimulate hybrid cell growth Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 4: 88-89
Goodman, J.W.; Shinpock, S.G.; Basford, N.L. 1979: Thymic involvement in control of bone marrow growth. use of T-cell-depleted hybrid mice Experimental Hematology 7(1): 17-26
Akiyama, S. 1985: The effect of calcium antagonists on intracellular transport of epidermal growth factor and the conjugate of epidermal growth factor with pseudomonas exotoxin Gan to Kagaku Ryoho. Cancer and ChemoTherapy 12(3 Part 2): 660-668
Zhao, Q. 1996: Mutagenesis of bovine basic fibroblast growth factor through hybrid clonemid construction: a new approach to DNA manipulation British Journal of Biomedical Science 53(4): 270-277
Heslop, B.F.; McNeilage, L.J. 1989: The F1 hybrid effect in allogeneic lymphocyte cytotoxicity. Points of similarity between hybrid resistance and ALC Transplantation 48(4): 634-639
Wit, J.M. 1988: Taller with growth hormones? Tijdschrift Voor Kindergeneeskunde 56(Suppl 1): 1-3
Vanderschueren-Lodeweyckx, M. 1993: Growth and hormones: from fetus to adult Revue Medicale de la Suisse Romande 113(3): 219-223
Ballard, F.J.; Nield, M.K.; Francis, G.L.; Knowles, S.E. 1981: Regulation of intracellular protein degradation by insulin and growth factors Acta Biologica et Medica Germanica 40(10-11): 1293-1300
Felt, V. 1973: Relationships between growth hormone and thyroid hormones in man Casopis Lekaru Ceskych 112(34): 1045-1049