Contraception with the lynestrenol "mini-pill."
Ravn, J.
Drug Research 22: 104-113
1972
ISSN/ISBN: 2194-9379 PMID: 12276428 Document Number: 489740
The efficacy of continuous treatment with the progestin Exluton (.5 mg/day lynestrenol) was evaluated in 361 women over a total of 3553 cycles. The treatment was 100% effective in preventing pregnancy. The length of the menstrual cycle and intensity of menstrual flow were not appreciably altered. Breakthrough bleeding and spotting were reported during the early stages of treatment, but the incidence of irregular bleeding dropped to an average of 2.4% of the cycles between the 4th and 12th cycles. Increased libido was reported by some patients, while headache appeared to occur less frequently. 4 women who desired to become pregnant, became pregnant within 6-10 weeks after discontinuing treatment. It is concluded that Exluton is a safe, reliable, and acceptable method of contraception.