Synthesis and antitumor activity of new heterocyclic 5-fluorouracil derivatives
Mao, M.; Chen, Y.; Tian, X.
Yao Xue Xue Bao 33(5): 389-391
1998
ISSN/ISBN: 0513-4870 PMID: 12017008 Document Number: 489620
Two new compounds I and II of 5-FU derivatives have been synthesized. The structures of the new compounds were confirmed by 1HNMR, MS, IR, UV and elemental analysis. The antitumor activities of compound I was tested against KB, HCT-8 and A2780. The preliminary results showed that the activity of compound I was stronger than that of HCFU and 5-FU.
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