Werner's syndrome
Haddad, F.; Debs, R.; Tohme, A.; Helou, J.; Ghayad, E.
Annales de Dermatologie et de Venereologie 125(1): 24-26
1998
ISSN/ISBN: 0151-9638 PMID: 9747202 Document Number: 489531
Werner's syndrome associates early aging in young adults, small height, cataract, glucose intolerance, hypogonadism, skin ulcers, vascular calcifications and osteoporosis. We report a new case of Werner's syndrome in a 34-year-old man with suggestive alterations of the skin and endocrine anomalies in addition to hypospadias, urethral stenosis, bilateral mega-ureter and chronic renal failure. The diagnosis of Werner's syndrome in our patient was unquestionable because of the clinical presentation and the familial context. However, the urology anomalies have not been reported in this syndrome. A simple coincidence cannot be excluded.