Determination of amphetamine derivatives in urine with solid phase micro-extraction (SPME)

Benkö, A.; Dona, A.; Kovács, A.; Maravelias, C.; Mikóné, H.Z.; Kerner, A.

Acta Pharmaceutica Hungarica 68(5): 269-275

1998


ISSN/ISBN: 0001-6659
PMID: 9805812
Document Number: 489494
Amphetamine derivatives (amphetamine A, methamphetamine MA, 3,4-methylene-dioxy-methamphetamine MDMA, 3,4-methylene-dioxy-amphetamine MDA and 3,4-methylene-dioxy-N-ethyl-amphetamine MDE) are the first most frequently group of abused illegal drugs in Hungary. This experimental work deals with in the determination of amphetamines in connection with the forensic toxicological applicability of a relatively new isolation process, the SPME using by GC-NPD analysis. The paper demonstrates 14 types of amphetamine investigation from spiked urine samples and reports two typical amphetamine cases for SPME isolation method.

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