Study of structure of secretory 28 kDa protein from the rat olfactory epithelium

Andreeva, S.G.; Merkulova, M.I.; Shuvaeva, T.M.; Novoselov, V.I.; Peshenko, I.V.; Novoselov, S.V.; Fesenko, E.E.; Lipkin, V.M.

Bioorganicheskaia Khimiia 24(11): 816-821

1998


ISSN/ISBN: 0132-3423
PMID: 10079938
Document Number: 489413
Clone lambda a26.1 isolated from rat olfactory epithelium contains a full-length 28-kDa protein cDNA (1414 b.p.). The reconstructed protein sequence comprises 223 aa with a calculated molecular mass of 24,630 Da. A substantial homology was revealed between the amino acid sequence of the 28-kDa protein and those of thiol-specific antioxidants (peroxiredoxines). The 28-kDa protein belongs to the 1 Cys-subfamily of peroxiredoxines and is the first member of peroxiredoxines identified in the olfactory epithelium.

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