Combined schedule of 7-valent pneumococcal conjugate vaccine followed by 23-valent pneumococcal vaccine in children and young adults with sickle cell disease

Vernacchio, L.; Neufeld, E.J.; Macdonald, K.; Kurth, S.; Murakami, S.; Hohne, C.; King, M.; Molrine, D.

Journal of Pediatrics 133(2): 275-278

1998


ISSN/ISBN: 0022-3476
PMID: 9709721
Document Number: 486413
We compared the immunogenicity of 7-valent pneumococcal-conjugate vaccine plus 23-valent pneumococcal vaccine to immunization with 23-valent vaccine only in individuals gtoreq2 years of age with sickle cell disease. IgG pneumococcal antibody concentrations were higher in the combined schedule group with no increase in side effects observed after immunization with 23-valent vaccine.

Document emailed within 1 workday
Secure & encrypted payments