Comparative clinical and morphological studies of 2 oral contraceptives containing DL-norgestrel or D-norgestre

Brosens, I.; Van Assche, A.; Wijnants, P.

Geburtshilfe und Frauenheilkunde 31(3): 251-257

1971


ISSN/ISBN: 0016-5751
PMID: 5550233
Document Number: 485953
Comparison of the effects of Eugynon and Neogynon (.05 mg ethinyl estradiol with .5 mg norgestrel or with .25 mg d-norgestrel, respectively) in 272 women is reported. The 2 preparations were comparable as regards effectiveness (100%), cycle control, and endometrial and cervical morphology. No clinical or biological complications occurred, and the incidence of minor side effects was very small. The d-norgestrel preparation (Neogynon) may be preferable for metabolic reasons because of its lower steroid dose.

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