The dynamics of aminotransferase activity in the blood plasma as a reflection of the characteristics of the pathological process in patients with craniocerebral trauma
Ivanov, D.E.; Melamud, E.E.; Puchin'ian, D.M.
Patologicheskaia Fiziologiia i Eksperimental'naia Terapiia 4: 6-8
1998
ISSN/ISBN: 0031-2991 PMID: 9951292 Document Number: 484182
The activity of alanin-aminotransferase (ALT) and aspartate-aminotransferase (AST) was measured in blood plasma of 103 patients with brain trauma. Sex-related differences were found. One day after the trauma ALT and AST activity rose significantly both in men and women with brain concussion, in males with mild and moderate brain contusion. In severe brain contusion the enzymes activity did not change. Eight days after the trauma AST activity significantly lowered in patients with brain concussion. No changes in aminotransferases activity one day after severe brain contusion evidence for biochemical maladaptation.