Treatment of postoperative alcohol withdrawal syndrome after esophageal resection
Huber, F.T.; Bartels, H.; Siewert, J.R.
Langenbecks Archiv für Chirurgie. Supplement Ii Verhandlungen der Deutschen Gesellschaft für Chirurgie. Deutsche Gesellschaft für Chirurgie. Kongress 1990: 1141-1143
1990
ISSN/ISBN: 0173-0541 PMID: 1983500 Document Number: 4824
Prophylaxis and treatment of alcohol withdrawal syndrome following esophagectomy consists of substitution with alcohol (1-2 g/kg/d), monotherapy with Midazolam (0.2-0.4 mg/kg/h) und Clonidin (1-2 mg/d). Out of 218 patients undergoing esophagectomy from X/86 till III/90 52 were classified as alcoholics and divided in 3 comparable groups. The Midazolamgroup showed the best results as far as withdrawal symptoms, time at the ICU, ventilation time, respiratory complications, delirium tremens and mortality are concerned. Patients in the Clonidin-group needed extensive supplimentary sedation.
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