Top Abstract Purchase Related
Home
>
Node
>
Subnode

Bioavailability and pharmacokinetics of desmopressin in elderly men

Hougaard, C.; Matthiesen, T.B.; Rittig, S.; Djurhuus, J.C.

Scandinavian Journal of Urology and Nephrology. Supplementum 183: 53-54

1997

ISSN/ISBN: 0300-8886
PMID: 9165608
Document Number: 478611
The bioavailability and pharmacokinetics of desmopressin (Minirin, DDAVP) have been studied in elderly males, aged between 55 and 75 years. In a four-way randomised study, subjects received a dose of desmopressin either intravenously (2 micrograms) or orally (200 micrograms) and either at 11 am or 10 pm. Daytime and night-time urine samples were collected both with and without desmopressin treatment. Intravenous doses of desmopressin were observed to have a longer duration of action than when the dose was given orally. These differences in efficacy may be attributable to differences in the bioavailability of desmopressin after intravenous or oral treatment.

Document emailed within 1 workday
Secure & encrypted payments

Lethagen, S.; Harris, A.S.; Sjörin, E.; Nilsson, I.M. 1987: Intranasal and intravenous administration of desmopressin: effect on F VIII/vWF, pharmacokinetics and reproducibility Thrombosis and Haemostasis 58(4): 1033-1036
Bron, J.; Vree, T.B.; Damsma, J.E.; Hekster, Y.A.; van der Kleijn, E. 1979: Dissolution, bioavailability and pharmacokinetics of three nitrofuratoin preparations in man Arzneimittel-Forschung 29(10): 1614-1620
Gao, S.; Liu, G.L.; Wang, S.X.; Gao, X.H. 1991: Pharmacokinetics and bioavailability of famotidine in 10 Chinese healthy volunteers Zhongguo Yao Li Xue Bao 12(3): 195-198
De Caro, L.; Ghizzi, A.; Costa, R.; Longo, A.; Ventresca, G.P.; Lodola, E. 1989: Pharmacokinetics and bioavailability of oral acetylcysteine in healthy volunteers Arzneimittel-Forschung 39(3): 382-386
Hutt, V.; Molz, K.H.; Pabst, G.; Dilger, C.; Mosberg, H.; Jaeger, H. 1989: Bioavailability and pharmacokinetics of a new nifedipine preparation in healthy volunteers Arzneimittel-Forschung 39(5): 607-611
Warneke, G.; Setnikar, I. 1993: Bioavailability and pharmacokinetics of fluoride from two glutamine monofluorophosphate preparations Arzneimittel-Forschung 43(5): 584-590
Yeh, K.C.; August, T.F.; Bush, D.F.; Lasseter, K.C.; Musson, D.G.; Schwartz, S.; Smith, M.E.; Titus, D.C. 1989: Pharmacokinetics and bioavailability of Sinemet CR: a summary of human studies Neurology 39(11 Suppl. 2): 25-38
Juhran, V.W.; Haase, W.; Götz, R.; Fleissig, W. 1975: The pharmacokinetics of papaverine and its bioavailability from a sustained-action preparation Arzneimittel-Forschung 25(5): 771-773
Maier-Lenz, H.; Ringwelski, L.; Windorfer, A. 1980: Pharmacokinetics and relative bioavailability of a nitroglycerin ointment formulation Arzneimittel-Forschung 30(2): 320-324
Hutt, V.; Pabst, G.; Salama, Z.; Kappler, J.; Jaeger, H. 1995: The pharmacokinetics and bioavailability of a new mexiletine preparation in healthy volunteers Arzneimittel-Forschung 45(3): 254-257
Rey, E.; d'Athis, P.; Richard, M.O.; de Lauture, D.; Olive, G. 1982: Pharmacokinetics of tiapride and absolute bioavailability of three extravascular forms International Journal of Clinical Pharmacology Therapy and Toxicology 20(2): 62-67
Puigdellívol, E.; Carral, M.E.; Moreno, J.; Plà-Delfina, J.M.; Jané, F. 1985: Pharmacokinetics and absolute bioavailability of intramuscular tranexamic acid in man International Journal of Clinical Pharmacology Therapy and Toxicology 23(6): 298-301
Gong, X.-h.; Zhao, M.-j.; Yuan, A.; Li, Y.; Xiong, L.; Peng, C.; Li, Y.-x. 2015: Pharmacokinetics and bioavailability study of neoline in Beagle dogs Zhongguo Zhong Yao Za Zhi 40(13): 2656-2660
Leucuta, S.; Pop, R.; Kory, M.; Toader, S.; Böhm, B.; Melian, E. 1979: Pharmacokinetics and bioavailability of lithium administered to dogs as monoglutamate and carbonate Pharmaceutica Acta Helvetiae 54(11): 343-346
Trenk, D.; Wagner, F.; Jähnchen, E.; Spahn, H.; Mutschler, E. 1987: Pharmacokinetics and bioavailability of piretanide in healthy volunteers following intramuscular administration Arzneimittel-Forschung 37(12): 1382-1385
Palma-Aguirre, J.A.; Rosas-Alcázar, G.; Rodríguez, J.M.; León-Urrea, F.; Montoya-Cabrera, M.A. 1989: Bioavailability and pharmacokinetics of nifedipine administered by different routes in healthy volunteers Archivos de Investigacion Medica 20(2): 129-135
Gandini, R.; Cunietti, E.; Assereto, R.; Castoldi, D.; Tofanetti, O.; Baggio, E. 1987: Pharmacokinetics and bioavailability of a new slow-release isosorbide-5-mononitrate system Cardiologia 32(11): 1287-1291
Bergan, T.; Leinebo, O.; Blom-Hagen, T.; Salvesen, B. 1984: Pharmacokinetics and bioavailability of metronidazole after tablets, suppositories and intravenous administration Scandinavian Journal of Gastroenterology. Suppl 91: 45-60
Gielsdorf, W.; Nieder, M.; Molz, K.H.; Jaeger, H.; Haerlin, R.; Radtke, H.W. 1986: The pharmacokinetics and bioavailability of urapidil. in vitro/in vivo correlations of different experimental formulations Arzneimittel-Forschung 36(8): 1265-1267
Simoni, P.; Sabatini, L.; Baraldini, M.; Mirasoli, M.; Roda, A.; Roda, E. 2002: Pharmacokinetics and bioavailability of four modified-release ursodeoxycholic acid preparations for once-a-day administration International Journal of Clinical Pharmacology Research 22(2): 37-45