A clinical trial of Neo Sampoon vaginal contraceptive tablets
Begum, S.F.; Liao, W.C.; McCann, M.F.; Ahmad, N.
Contraception 22(6): 573-582
1980
ISSN/ISBN: 0010-7824 PMID: 7214907 DOI: 10.1016/0010-7824(80)90084-0Document Number: 447693
In mid-1978, the International Fertility Research Program initiated a clinical trial of Neo Sampoon Loop vaginal tablet contraceptives. Data were recorded on standardized forms in several countries. The Bangladesh study was conducted at the Dacca Medical College Hospital. Results from the Bangladesh study are discussed and tabulated. The study showed good acceptability of this method. Of the 150 women enrolled in the study, 115 were still in it after 12 months. After 12 months, there was a 6.5/100 women pregnancy rate and a 24.8/100 women discontinuation rate. These rates are encouraging since most of the women had no previous experience with barrier contraception. Discomfort and a burning sensation were the main reasons for discontinuance. This method can be easily distributed outside the medical system, a system which will be necessary if all at-risk people in the world are to be covered. The fact that regularity of use fell off by 12 months indicates that sustaining motivation may be the main problem with this method of contraception.