Anesthesia with sevoflurane vs propofol in elective extracavity surgery
Cetica, P.; Falchi, S.; Falsini, S.; Girardi, G.; Melani, A.M.; Pieraccioli, E.; Novelli, G.P.
Minerva Anestesiologica 63(1-2): 47-56
1997
ISSN/ISBN: 0375-9393 PMID: 9213839 Document Number: 474792
To compare the cardiovascular effects and recovery characteristics of sevoflurane and propofol anesthesia in 80 ASA I and II patients undergoing elective extracavity surgery expected to last at least one hour. A prospective randomized clinical trial. After meperidine and atropine premedication, the patients were randomly allocated into two groups: in the sevoflurane group thiopentone was administered for induction of anesthesia and sevoflurane for maintenance; the propofol group received propofol either for induction of anesthesia or maintenance. All patients received N2O, vecuronium, artificial ventilation and fentanyl as needed. Vital parameters were monitored during anesthesia and two hours later. Recovery times were recorded after anesthesia. Statistical analysis was performed with SAS (Statistical Analysis System). In the sevoflurane group, heart rate and diastolic pressure were slightly higher than in the propofol group. Recovery time was faster after sevoflurane anesthesia.