Treatment of thoracic esophageal carcinoma which invades adjacent structure--significance of resection and combined therapy
Fukumoto, T.; Kijima, F.; Shimada, M.; Kusano, C.; Yoshinaka, H.; Baba, M.; Aikou, T.
Nihon Kyobu Geka Gakkai 45(5): 732-741
1997
ISSN/ISBN: 0369-4739 PMID: 9170866 Document Number: 474527
From January 1980 to December 1994, a total of 64 cases of thoracic esophageal carcinoma which invaded adjacent structure (A3) were resected and 35 cases were unresected in Kagoshima University Hospital. Adjacent structures were mainly trachea/bronchus, aorta or pulmonary vein. Combined resections were performed in 22 cases (34.4%), and no tumors remained in 12 cases (18.8%). One year survival rates and 50% survival time of the no residual tumor group were 25.7% and 8.5 months, while the rates of the residual tumor group were 15.7% and 5.1 months. But, there was no significant difference of survival rates according to the amount of residual tumor. On the other hand, 1-year survival rates and 50% survival time of unresected group were 3.1% and 4.5 months. As a postoperative adjuvant therapy, radiation was the most effective modality. As a result, operations should be done at first for the A3 carcinoma in which a complete combined resection is expected. On the other hand, radiation or chemotherapy should be selected for the cases in which the tumor may remain, even though combined resection is done.