Sulfurtransferases activity and the level of low-molecular-weight thiols and sulfane sulfur compounds in cortex and brain stem of mouse
Wróbel, M.; Włodek, L.; Srebro, Z.
Neurobiology 4(3): 217-222
1996
ISSN/ISBN: 1216-8068 PMID: 9044347 Document Number: 467894
The level of 3-mercaptopyruvate sulfurtransferase (MPST) and rhodanese activity and the level of sulfane sulfur compounds, L-cysteine and non-protein sulfhydryl groups (NPSH) were compared in cortex and brain stem of mouse. The level of cysteine and sulfane sulfur compounds was higher in brain stem; 107% and 217% of the value determined in cortex, respectively. The activity of MPST and rhodanese showed also increased level in brain stem; 114% and 119% of the value determined in cortex, respectively. The level of NPSH in cortex was about 10% higher in comparison to brain stem. It seems that in brain stem metabolism of sulfane sulfur compounds and/or their accumulation may occur in a higher degree than in cortex.