Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effects of histamine H2-receptor blockers and dalargin on reparative processes gastroduodenal mucosa in patients with duodenal ulcer

Alekseenko, S.A.; Timoshin, S.S.

Klinicheskaia Meditsina 74(9): 52-54

1996

ISSN/ISBN: 0023-2149
PMID: 9121092
Document Number: 467533
The effect of synthetic opiate peptide dalargin, histamine H2-receptors blockers (cimetidin, famotidin) and combination of dalargin with famotidin on proliferative activity of gastroduodenal mucosal epithelium has been studied autoradiographically (3H-thymidine) in 75 patients with duodenal ulcer. Compared to spasmolytics and antacids, the studied drugs (dalargin, cimetidin and famotidin) significantly increased the number of DNA-synthetizing cells in the epithelium of fundal stomach, duodenal cap and ulcer borders. Maximal effect was noticed in combined use of dalargin and famotidin. A correlation existed between clinical and stimulating reparative effect of the drugs.

Document emailed within 1 workday
Secure & encrypted payments

Belousov, A.S.; Leont'eva, G.V.; Rakitskaia, L.G.; Kolesova, O.E.; Lebkova, N.P.; Akhmad Khzhuzh 1990: Effects of cimetidine, a H2-histamine blocker, on ulcer cicatrization processes in patients with peptic ulcer localized in the duodenal bulb Klinicheskaia Meditsina 68(3): 96-99
Spasov, A.A.; Chernikov, M.V.; Speranskaia, A.S.; Zaĭchenko, S.I. 2005: Gastroprotective effects of histamine H2-receptor blockers in Helicobacter-like gastric mucosa lesions Eksperimental'naia i Klinicheskaia Gastroenterologiia 6: 24-27; 111-112
Gil'miiarova, F.N.; Tutel'ian, V.A.; Radomskaia, V.M.; Gapparov, M.M.; Kuznetsova, O.I.; Babichev, A.V.; Kleĭman, M.S.; Vinogradova, L.N.; Baisheva, G.M.; Gerge', N.I.; Gil'miiarov, E.M. 2001: Effect of biologically active components of natursil on the course of reparative processes in the gastrointestinal mucosa in experiments and in patients with stomach and duodenal ulcers Voprosy Pitaniia 70(5): 29-34
Perakath, B.; Sitaram, V.; Khanduri, P.; Richard, J. 1999: Duodenal ulcer perforation: have H2 receptor blockers reduced mortality? Tropical Gastroenterology: Official Journal of the Digestive Diseases Foundation 20(1): 53-54
Bardhan, K.D. 1991: Will omeprazole succeed in refractory duodenal ulcer when the histamine receptor antagonists fail? National Medical Journal of India 4(3): 130-131
Relan, N.K.; Fligiel, S.E.; Dutta, S.; Tureaud, J.; Chauhan, D.P.; Majumdar, A.P. 1995: Induction of EGF-receptor tyrosine kinase during early reparative phase of gastric mucosa and effects of aging Laboratory Investigation; A Journal of Technical Methods and Pathology 73(5): 717-726
Koval'chuk, L.A. 1985: Regional blood flow in the gastric and duodenal mucosa of duodenal ulcer patients before and after selective proximal and truncal vagotomies Klinicheskaia Khirurgiia 8: 10-12
Lukash, N.V.; Polishchuk, T.F. 1995: The effect of thymalin, dalargin and "Mucosalin" on the course of an experimental duodenal ulcer Likars'ka Sprava 1995(1-2): 53-55
Dajani, E.Z.; Penin, V.A.; Sokolov, L.K.; Vahtangishvilli, R.; Bogdanov, A.; Afonskaya, N.; Ivanishvilli, L.; Zharova, Y.; Efremova, I. 1991: Misoprostol and dalargin for the inpatient treatment of duodenal ulcer in the USSR Journal of the Association for Academic Minority Physicians: the Official Publication of the Association for Academic Minority Physicians 2(1): 18-22
Krylovskiĭ, S.I. 1982: Changes in histamine metabolism in patients with perforated stomach and duodenal ulcer Khirurgiia 1982(12): 61-63
Domschke, W.; Subramanian, N.; Mitznegg, P.; Baenkler, H.W.; Domschke, S.; Wünsch, E. 1977: Gastric mucosal histamine in duodenal-ulcer patients: release by secretin Acta Hepato-Gastroenterologica 24(6): 444-446
Hustin, J.; Lagneaux, G.; Donnay, M.; Debongnie, J.C. 1994: Cytologic patterns of reparative processes, true dysplasia and carcinoma of the gastric mucosa Acta Cytologica 38(5): 730-736
Lombardo, L.; Colombatti, G.; Babando, G.M.; Genovesio, L.; Riccardino, N. 1984: Digestive mycotic contamination in patients with duodenal ulcer after treatment with histamine H2 antagonists Recenti Progressi in Medicina 75(1): 19-27
Cheret, A.M.; Pignal, F.; Lewin, M.J. 1981: Effects of H2-receptor antagonists cimetidine, ranitidine, and ICi 125,211 on histamine-stimulated adenylate cyclase activity in guinea pig gastric mucosa Molecular Pharmacology 20(2): 326-330
Kronborg, O. 1970: Pre- and postoperative insulin tests in patients with duodenal ulcer. Comparison with the augmented histamine test Scandinavian Journal of Gastroenterology 5(8): 687-693
Desai, H.G.; Zaveri, M.P.; Mohalla, D.J.; Antia, F.P. 1970: Acid output in control subjects and patients with duodenal ulcer using fixed doses of histamine Indian Journal of Medical Research 58(1): 33-38
Miagkova, L.P.; Alekperov, R.T. 1991: Status of the immune system and the reparative processes in peptic ulcer Klinicheskaia Meditsina 69(8): 26-30
Ribet, A.; Balas, D.; Bastie, M.J.; Senegas-Balas, F.; Escourrou, J.; Bommelaer, G.; Pradayrol, L. 1981: Long term effects of H2-receptor antagonists (cimetidine and ranitidine) on the human gastric and duodenal mucosa Scandinavian Journal of Gastroenterology. Suppl 70: 155-174
Esenin, V.I.; Sokolova, G.N.; Gorodinskaia, V.S. 1975: Secretory-motor function and the state of duodenal mucosa in duodenal ulcer and duodenitis Klinicheskaia Meditsina 53(6): 90-99
Manevska, B.; Zlateva, M.; Marinov, M. 1976: Morphological changes in the gastric and duodenal mucosa in duodenal ulcer in young persons Vutreshni Bolesti 15(3): 68-73