Antiinflammatory activity of topically applied sertaconazole nitrate
Agut, J.; Tarrida, N.; Sacristán, A.; Ortiz, J.A.
Methods and Findings in Experimental and Clinical Pharmacology 18(4): 233-234
1996
ISSN/ISBN: 0379-0355 PMID: 8803954 Document Number: 458192
The antiinflammatory activity of topically applied sertaconazole nitrate was investigated. The dermal administration of 2% sertaconazole to rats, in which edema was induced by application of croton oil in the external ear, induced a 39.8% reduction of edema. The results show that sertaconazole applied by a topical route at the concentration at which it is used in clinic, has antiinflammatory action in this experimental model.