Brain glycolipids in rats after disulfiram administration
Selevich, M.I.; Lelevich, V.V.
Eksperimental'naia i Klinicheskaia Farmakologiia 59(5): 47-48
1996
ISSN/ISBN: 0869-2092 PMID: 9026211 Document Number: 457386
The effect of disulfiram (teturam, antabus) (200 mg/kg, intragastrically) on the rat brain glycolipid structure was studied. It was found that disulfiram increased the contents of cerebrosides I and III in nervous tissue. The administration of alcohol (1 g/kg, 20% solution, intraperitoneally), with disulfiram being simultaneously administered, was accompanied by increased levels of brain cerebrosides I and II.
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