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Serum levels of sCD23 and IL-4 concentration in stimulated PBMC in children with atopic diseases

Boznański, A.; Machnicki, M.; Willak-Janz, E.

Pediatria Polska 71(9): 753-757

1996

ISSN/ISBN: 0031-3939
PMID: 8927482
Document Number: 455344
In this study we estimated the correlation between IgE and sCD23 serum levels, and the concentration of IL-4 in PHA-stimulated PBMC cultures in children with atopic diseases. Children with atopic dermatitis showed a high degree of correlation between sCD23-IgE while in the control group no such relationship was found. We also found no relationship between IL-4 and sCD23 in children with atopic asthma, relationship at children with atopic dermatitis, and no relationship in healthy children. Looking for relationship between IL-4 in PHA-stimulated PBMC and IgE serum levels we discovered a weak negative correlation in children with atopic asthma, a highly positive correlation in children with atopic dermatitis and no relationship in the control group.

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