Role of immunological factors in peripheral vitreo-chorioretinal dystrophies and macular ruptures of the retina
Balashova, L.M.; Saksonova, E.O.; Zaĭtseva, N.S.; Slepova, O.S.; Teplinskaia, L.E.; Il'nitskiĭ, V.V.; Grishin, V.L.
Vestnik Oftalmologii 111(1): 16-18
1995
ISSN/ISBN: 0042-465X PMID: 7771035 Document Number: 453921
The authors analyze the results of clinical and immunological examinations of patients with peripheral vitreo-chorioretinal dystrophies (PVCRD) and macular ruptures of the retina. No antibodies to S-AG were detected in the lacrimal fluid in 87.5% of patients with PVCRD without retinal defects. In patients with PVCRD with retinal defects antibodies to S-AG were detected in 70% of cases. These antibodies were absent in the patients with macular ruptures of the retina. In none of the patients were these antibodies detected in the blood serum. The levels of circulating immune complexes were normal in the patients PVCRD and increased in those with macular ruptures of the retina. These data permit a hypothesis on the development of local autoimmune reactions in PVCRD patients in response to the appearance of AG of the injured tissues.