Beta-Adrenoceptor agonists-induced desensitization in rat trachea
Vassilev, P.P.
Acta Physiologica et Pharmacologica Bulgarica 21(3): 57-62
1995
ISSN/ISBN: 0323-9950 PMID: 8868367 Document Number: 453114
The development and the characteristics of beta-adrenoceptor agonists-induced desensitization in rat trachea were studied. Tracheal strips were contracted with carbachol and cumulative concentration-response curves for various beta-adrenoceptor agonists were constructed before and after 30-min incubation either with the same beta-adrenoceptor agonist or with another beta-adrenoceptor agonist. Some problems of the in vitro desensitization in rat trachea were also considered.
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