Sensory ataxic neuropathy associated with Sjögren's syndrome
Yasuda, T.; Kumazawa, K.; Sobue, G.
Nihon Rinsho. Japanese Journal of Clinical Medicine 53(10): 2568-2573
1995
ISSN/ISBN: 0047-1852 PMID: 8531375 Document Number: 451481
One tenth of patients with Sjögren's syndrome (SS) is associated with peripheral neuropathy. Trigeminal neuropathy, mononeuropathy multiplex, sensory neuropathy, distal sensory neuropathy, ataxic sensory-autonomic neuropathy have been described as the neuropathy associated with SS. However, some of them secondary occur associated with the vasculopathy due to rheumatoid arthritis, systemic lupus erythematodes etc combined with SS. We demonstrated the clinico-patho-physiological features and spinal MRI findings of patients with primary SS in whom the sensory ataxia and autonomic dysfunctions were the predominant symptoms. The underlying pathology was lymphocytic (T cells) infiltration to the dorsal root ganglia with sensory neuronal degeneration. These findings have identified as association between SS and sensory ataxic neuropathy.