Sensory neuropathy with low-dose pyridoxine
Parry, G.J.; Bredesen, D.E.
Neurology 35(10): 1466-1468
1985
ISSN/ISBN: 0028-3878 PMID: 2993949 Document Number: 245374
In 16 patients with neuropathy associated with pyridoxine abuse, the clinical picture of a pure sensory central-peripheral distal axonopathy was consistent. Pyridoxine dose was 0.2 to 5 g daily and duration of ingestion before symptoms was inversely proportional to the daily intake. In all patients with adequate follow-up, improvement followed discontinuation of pyridoxine. The ready availability of up to 1-g tables makes it likely that this neuropathy will continue to be seen.