A study of postpill amenorrhea
Chatterjee, R.; Banerjee, S.; Ghosh, K.K.; Chaudhuri, N.
International Journal of Gynaecology and Obstetrics the Official Organ of the International Federation of Gynaecology and Obstetrics 18(2): 113-114
1980
ISSN/ISBN: 0020-7292 PMID: 6108247 DOI: 10.1002/j.1879-3479.1980.tb00258.xDocument Number: 451318
Levels of follicle-stimulating hormone, luteinizing hormone, and prolactin were evaluated in 52 cases of post oral contraceptive (OC) amenorrhea in an effort to determine the causes, the prognosis and the treatment of this entity. The cases were selected from patients with postpill amenorrhea at the Seth Suklal Karnani Memorial Hospital in Calcutta, India. The patients were instructed to report to the hospital with empty stomachs. Follicle-stimulating hormone (FSH), luteinizing hormone (LH), and prolactin (PRL) levels were estimated by radioimmunoassay, using the double-antibody technique. Gonadotropin and prolactin profiles were undertaken in 72 control patients who were in different parts of the menstrual cycle. Routine histories were taken and clinical examinations, roentgenograms of the pituitary fossa and thyroid function tests were performed. The incidence of postpill amenorrhea was much higher in patients with histories of oligomenorrhea or irregular menstrual periods. There was no relationship between the number of cycles of OCs used and the incidence of postpill amenorrhea. The ratio of LH to FSH in all cases exceeded unity, indicating that postpill amenorrhea is a type of functional secondary amenorrhea.
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