Serum prolactin levels in postpill amenorrheic patients
Karaman, A.S.; Uran, B.; Erler, A.
International Journal of Gynaecology and Obstetrics the Official Organ of the International Federation of Gynaecology and Obstetrics 43(2): 177-180
1993
ISSN/ISBN: 0020-7292 PMID: 7905434 DOI: 10.1016/0020-7292(93)90326-rDocument Number: 336267
OBJECTIVES: In this study, we evaluated the importance of the determination of serum prolactin levels in postpill amenorrheic patients. METHODS: Serum estradiol and prolactin levels were determine in 37 postpill amenorrheic patients. Bromocriptine was administered to the hyperprolactinemic group and clomiphene citrate to the normoprolactinemic group. RESULTS: Hyperprolactinemia was observed in 21 patients (56.7%) and serum estradiol levels lt 50 pg/ml were found in 19 of these patients. The mean prolactin level was 71.90 +- 23.05 ng/ml in the hyperprolactinemic group. While bromocriptine had a significant effect on the length of time for menstrual bleeding to return (P lt 0.001), clomiphene had no effect. CONCLUSIONS: No treatment is required to the postpill amenorrheic patients with normal estradiol and prolactin levels. If hyperprolactinemia is detected, bromocriptine may be used as a treatment to promote normal menstrual bleeding and ovulation.