Distribution of the HLA-DQA1 polymorphism in the population of the Basque Country (Spain)

Esparza, B.; Pestoni, C.; Martin, M.D.; Merino, F.; Carracedo, A.

Gene Geography a Computerized Bulletin on Human Gene Frequencies 9(1): 53-58

1995


ISSN/ISBN: 0394-249X
PMID: 8845339
Document Number: 443785
Allele and genotype frequencies at the HLA-DQA1 locus were determined in Basque Country populations using PCR methodology and a dot-blot assay with ASO probes. The results showed no deviation from the Hardy-Weinberg equilibrium. No differences were found between the three Basque Provinces, but gene frequencies were significantly different from those of some other Spanish and world populations.

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