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Preoperative factors of prognostic significance in gastric cancer

Johnson, H.; Belluco, C.; Masood, S.; Azama, A.; Kahn, L.; Wise, L.

Journal of the National Medical Association 87(6): 423-426

1995

ISSN/ISBN: 0027-9684
PMID: 7595964
Document Number: 443027
This study was undertaken to investigate the ability of local anatomical and primary histological features of gastric cancers, as well as DNA analysis, to predict prognosis. Using multivariate analysis, results indicate that location of a tumor in the gastric cardia, poor differentiation, involvement of adjacent organs, and aneuploidy are all independent predictors of survival. All of the factors studied can be determined by endoscopic procedures preoperatively on patients with gastric cancers and could be helpful in selecting some patients for perioperative adjunctive therapies.

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