Determination of ephedrine, pseudoephedrine, and norephedrine in mixtures (bulk and dosage forms) by proton nuclear magnetic resonance spectroscopy
Hanna, G.M.
Journal - Association of Official Analytical Chemists 78(4): 946-954
1995
ISSN/ISBN: 0004-5756 PMID: 7580334 Document Number: 441848
A simple, specific and accurate NMR spectroscopic method is presented for the quantitative determination of Ephedra alkaloids (-)-ephedrine, (+)-pseudoephedrine, and (+or-)-norephedrine, either singly or in mixtures with each other. Determination of individual compounds was carried out in D2O solution, with acetamide as internal standard.
Document emailed within 1 workday
Related Documents
Mountford, C.E.; Grossman, G.; Reid, G.; Fox, R.M. 1982: Characterization of transformed cells and tumors by proton nuclear magnetic resonance spectroscopy Cancer Research 42(6): 2270-2276de Certaines, J.D.; Nadal, L.; Leray, G.; Serrai, H.; Lewa, C.J. 1996: Proton nuclear magnetic resonance spectroscopy of plasma lipoprotein: technical problems and potential interest in cancer disease Anticancer Research 16(3b): 1451-1460
Nadal, L.; Leray, G.; Desbarats, C.; Darcel, F.; Bansard, J.Y.; Bondon, A.; de Certaines, J.D. 1997: Proton and phosphorus nuclear magnetic resonance spectroscopy of human brain tumor extracts with automatic data classification: a preliminary study Cellular and Molecular Biology 43(5): 659-673
Hanna, G.M.; Lau-Cam, C.A. 1989: Determination of diastereomeric purity of tranylcypromine sulfate by proton magnetic resonance spectroscopy with lanthanide shift reagent Journal - Association of Official Analytical Chemists 72(4): 556-558
Zhang, C.-Y.; Zhang, N.; He, L. 2014: Quantitative determination of bosentan by proton nuclear magnetic resonance with internal standard method Yao Xue Xue Bao 49(2): 249-251
Batista, I.A.S.d.A.; Gonçalves, M.I.ês.d.A.; Singh, A.K.; Hackmann, E.R.M.K.; Santoro, M.I.ês.R.M. 2008: Quantitative determination of dimethylaminoethanol in cosmetic formulations by nuclear magnetic resonance spectroscopy Journal - Association of Official Analytical Chemists 91(6): 1303-1308
Song, S.K.; Hotchkiss, R.S.; Neil, J.; Morris, P.E.; Hsu, C.Y.; Ackerman, J.J. 1995: Determination of intracellular calcium in vivo via fluorine-19 nuclear magnetic resonance spectroscopy American Journal of Physiology 269(2 Pt 1): C318-C322
Maerten, G.; Haberland, G. 1970: Place determination of acetyl-groups in acetates of digoxin by nuclear magnetic resonance spectroscopy Arzneimittel-Forschung 20(3): 347-351
Wainer, I.W.; Schneider, L.C.; Weber, J.D. 1981: Application of chiral lanthanide nuclear magnetic resonance shift reagents to pharmaceutical analysis. II. Determination of dextro- and levoamphetamine mixtures Journal - Association of Official Analytical Chemists 64(4): 848-850
Metarugcheep, P.; Hanchaiphiboolkul, S.; Viriyavejakul, A.; Chanyawattiwongs, S. 2012: The usage of proton magnetic resonance spectroscopy in Parkinson's disease Journal of the Medical Association of Thailand 95(7): 949-952
Meladze, N.V.; Kuchuk, P.V.; Abduraimov, A.B.; Les'ko, K.A.; Shariia, M.A.; Malik, D.S.; Matkhev, S.; Boĭko, E.A. 2011: Proton magnetic resonance spectroscopy in the diagnosis of breast cancer Vestnik Rentgenologii i Radiologii 4: 31-36
Tiutin, L.A.; Pozdniakov, A.V.; Stukov, L.A. 1999: Proton magnetic resonance spectroscopy in the diagnosis of brain diseases Vestnik Rentgenologii i Radiologii 5: 4-6
Naruse, S.; Tanaka, C. 1991: Proton magnetic resonance spectroscopy and chemical shift imaging Nihon Rinsho. Japanese Journal of Clinical Medicine 49(7): 1645-1655
Hsu, Y.Y.; Chang, C.N.; Chu, N.S.; Chang, C.; Hsu, J.C. 1997: Proton magnetic resonance spectroscopy in patients with complex partial seizures Journal of the Formosan Medical Association 96(8): 593-598
Pozdniakov, A.V.; Kartashev, A.V.; Tiutin, L.A.; Vinogradov, V.M.; Pozharisskiĭ, K.M. 2008: Proton magnetic resonance spectroscopy in postoperative radiochemotherapy of patients with cerebral glioblastoma Voprosy Onkologii 54(2): 164-169
Pozdniakov, A.V.; Tiutin, L.A.; Bisaga, G.N.; Odinak, M.M. 2001: Proton magnetic-resonance spectroscopy in remitting and secondary-progressive multiple sclerosis Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 101(4): 36-39
Bakunovich, A.V.; Sinitsyn, V.E.; Mershina, E.A. 2014: Clinical use of proton magnetic resonance spectroscopy in brain tumors and adjacent tissues Vestnik Rentgenologii i Radiologii 1: 39-50
Bertinotti, L.; Mortilla, M.; Conforti, M.Letizia.; Colangelo, N.; Nacci, F.; Del Rosso, A.; Fonda, C.; Casale, R.; Matucci-Cerinic, M.; Pignone, A. 2006: Proton magnetic resonance spectroscopy reveals central neuroaxonal impairment in systemic sclerosis Journal of Rheumatology 33(3): 546-551
Cox, I.J. 1988: Nuclear magnetic resonance spectroscopy British Journal of Hospital Medicine 40(3): 165
Hsu, Y.Y.; Chang, C.N.; Chu, N.S.; Lim, K.E.; Chang, C.; Hsu, J.C. 2001: Lateralization and prognostic value of proton magnetic resonance spectroscopy in patients with intractable temporal lobe epilepsy Chang Gung Medical Journal 24(12): 768-778