Modern representations of multiple forms of cyclic nucleotide phosphodiesterases in mammalian tissues
Medvedeva, M.V.
Biokhimiia 60(3): 364-386
1995
ISSN/ISBN: 0320-9725 PMID: 7734612 Document Number: 441736
The literary data from the past 10-15 years concerning cyclic nucleotide phosphodiesterase from animal tissues have been reviewed. The major properties of multiple forms of the enzyme differing in the mode of regulation, substrate specificity, physico-chemical parameters and primary structure are compared. The possible physiological role of the main phosphodiesterase forms and ways of their pharmacological regulation are discussed.