Biochemical markers of nutrition in type-i and type-Ii osteoporosis
Rico, H.; Relea, P.; Crespo, R.; Revilla, M.; Villa, L.F.; Arribas, I.; Usabiaga, J.
Journal of Bone and Joint Surgery. British Volume 77(1): 148-151
1995
ISSN/ISBN: 0301-620X PMID: 7822374 Document Number: 441137
We studied nutritional deficits, using as markers the levels of transferrin, retinol-binding protein, and prealbumin, in 20 women with osteoporotic hip fractures (type II), 40 women with vertebral fractures (type I), and two groups of age-matched control subjects. The concentrations of all three nutritional markers were lower in the two groups of patients than in their matched controls, and in type-I as compared with type-II osteoporosis. In the osteoporotic patients, simple linear regression showed a significant correlation between the variables which we studied (r2 ranged from 0.5 to 0.7; p < 0.001), the best correlation being between prealbumin and retinol-binding protein in type-II osteoporosis. Our results suggest that there is a more marked nutritional deficit in type-II than in type-I osteoporosis.