Promotion of aflatoxin-induced hepatoma growth in trout by methyl malvalate and sterculate
Lee, D.J.; Wales, J.H.; Sinnhuber, R.O.
Cancer Research 31(7): 960-963
1971
ISSN/ISBN: 0008-5472 PMID: 4327087 Document Number: 44004
These studies were prompted by the observation that seed oils containing cyclo-propenoid fatty acids, in particular malvalic and sterculic acids (present in the triglycerides of plants of the order Malvales) stimulate the incidence and growth of trout liver tumours induced by aflatoxin B1. Methyl sterculate, fed at the same time as aflatoxin B1, increased both the incidence and size of hepatomas in young rainbow trout.
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