Effect of paradentium polypeptide on the lipid peroxidation of the membranes and coagulation of erythrocytes in rats with spontaneous paradentitis
Silenko, I.I.; Vesnina, L.E.; Mishchenko, V.P.
Fiziolohichnyi Zhurnal 40(2): 88-91
1994
ISSN/ISBN: 2522-9028 PMID: 7758611 Document Number: 436646
The influence of alkaline polypeptides-cytomedines on the level of free radical oxidation of lipids, hemocoagulant, fibrinolytic and aggregative properties of erythrocytes in spontaneous parodontitis has been investigated. It has been established that the development of spontaneous parodontitis is accompanied by the activation of peroxide oxidation of cellular membranes, which results in the development of hypercoagulation and inhibition of fibrinolytic properties of erythrocytes, thereby intensifying the state of microcirculatory hemostasis. Polypeptide of the parodontium a modulating effect on the state of free-radical oxidation, improves antioxidant status of blood cells, stabilizes indices of erythrocytic link of hemostasis. The investigated cytomedines may be promising for treatment of the parodontium pathology.