Discovery, mechanism and expected clinical significance of selective cytotoxicity of 2-chloro-2'-deoxyadenosine (2-CdA)
Grieb, P.
Archivum Immunologiae et Therapiae Experimentalis 42(1): 1-5
1994
ISSN/ISBN: 0004-069X PMID: 7503624 Document Number: 435555
2-Chloro-2'-deoxyadenosine (2-CdA) is a new promising antileukemic and immunosuppressive agent. Discovery of 2-CdA and its unique properties, methods of synthesis, data explaining mechanism of its selective cytotoxicity, and current clinical status of the drug are briefly reviewed.
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