Effects of anterior hypothalamic deafferentation on LH, FSH, prolactin and sexual behavior in the ovariectomized ewe

Thiery, J.C.; Signoret, J.P.; Blanc, M.; Pelletier, J.; Ravault, J.P.; Caraty, A.; Lavenet, C.; Orgeur, P.; Potrier, J.C.; Venier, G.; Thiery, J.C; Signoret, J.P; Blanc, M; Pelletier, J; Ravault, J.P; Caraty, A; Lavenet, C; Orgeur, P; Potrier, J.C; Venier, G

Home

>

Node

>

Subnode

Effects of anterior hypothalamic deafferentation on LH, FSH, prolactin and sexual behavior in the ovariectomized ewe

Thiery, J.C.; Signoret, J.P.; Blanc, M.; Pelletier, J.; Ravault, J.P.; Caraty, A.; Lavenet, C.; Orgeur, P.; Potrier, J.C.; Venier, G.

Ircs Medical Science Reproduction Obstetrics and Gynecology 5(9): 434

1977

ISSN/ISBN: 0305-6929

PMID: 12260241

Document Number: 435204

The effects of anterior hypothalamic deafferentation on luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), and sexual behavior in the ovariectomized ewe was investigated. Response to injection of estradiol benzoate (50 mcg) was measured before and after surgery. In all 4 cases the estradiol-induced release of LH and PRL observed prior to surgery was eliminated after deafferentation. FSH and basal-PRL levels were also affected. After 3 months, 2 ewes showed partial recovery. Sexual behavior was eliminated in 2 cases. In the ewe, the anterior dorsal inputs from the preoptic anterior hypothalamus are required for the positive feedback of estrogens on LH and maintenance of FSH levels.