Intraoperative fluid therapy during experimental laparotomy of long duration
Isosu, T.
Masui. Japanese Journal of Anesthesiology 43(9): 1314-1321
1994
ISSN/ISBN: 0021-4892 PMID: 7967025 Document Number: 434396
Intraoperative fluid therapy was studied using 18 adult mongrel dogs in which laparotomy of long duration was performed. The 18 mongrel dogs were divided into three groups (Group I: lactated Ringer solution (LR) infused at the rate of 10 ml cntdot kg-1 cntdot h-1, Group II : LR infused at the rate of 20 ml cntdot kg-1 cntdot h-1, Group III : LR infused at the rate of 5 ml cntdot kg-1 h-1 and Salinhes infused at the rate of 5 ml cntdot kg-1 cntdot h-1). The differences in hemodynamic status, plasma colloid osmotic pressure, O-2 delivery, O-2 consumption et al were investigated in the three groups. Mean arterial pressure, cardiac output and renal blood flow were maintained in all groups. In group 1, skin blood flow decreased and O-2 extraction ratio started to increase four hours later suggesting that there is trouble in the balance of O-2 delivery and consumption. In group II, skin blood flow and urine volume were maintained, but plasma colloid os motic pressure was lowest in this group. In group III, skin blood flow volume decreased as it did in group I, but plasma colloid osmotic pressure was maintained at a higher level than that in the two other groups, and O-2 extraction ratio showed no significant changes. These findings indicate that colloid solution is useful for laparotomy of long duration. In conclusion, colloid solution should be added to the fluid used in laparotomy of long duration.