Long-term stability of diazepam injections
Fyllingen, G.; Kristiansen, F.; Roksvaag, P.O.
Pharmaceutica Acta Helvetiae 66(2): 44-46
1991
ISSN/ISBN: 0031-6865 PMID: 1758892 Document Number: 4314
Diazepam and its main degradation product 2-methyl-amino-5-chlorobenzophenon (MACB) were quantitatively determined by HPLC and spectrophotometry in one- to ten-years-old diazepam injections. The content of diazepam was within the specifications in all the samples. Not more than 1.5% degradation of diazepam was found after ten years.
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