Red cell glucose-6-phosphate dehydrogenase deficiency and haemoglobin variants among ten endogamous groups of Maharshtra and West Bengal
Kate, S.L.; Mukherjee, B.N.; Malhotra, K.C.; Phadke, M.A.; Mutalik, G.S.; Sainani, G.S.
Human Genetics 44(3): 339-343
1978
ISSN/ISBN: 0340-6717 PMID: 730172 DOI: 10.1007/bf00394299Document Number: 426252
Over 900 individuals from ten endogamous groups in the Indian states of Maharashtra and West Bengal were studied for G-6-PD deficiency and haemoglobin variants. The incidence of G-6-PD varied from nil to 17.3%, while that of Hb-S varied from nil to 22.3%. In general, the tribal populations of Maharashtra are characterized by the presence of a high incidence of both Hb-S and G-6-PD deficiency. The caste Hindus showed an absence of Hb-S and rather low G-6-PD deficiency. Immigrant Parsis possessed the highest incidence of G-6-PD deficiency (17.3%).