Thrombotic thrombocytopenic purpura associated with HIV infection: report of two cases
Nosari, A.M.; Landonio, G.; Caggese, L.; Cattaneo, D.; Muti, G.; Volonterio, A.
Haematologica 79(3): 280-282
1994
ISSN/ISBN: 0390-6078 PMID: 7926981 Document Number: 425129
We report two cases of thrombotic thrombocytopenic purpura (TrP) in advanced stage HIV-positive patients (CD4+ lt 0.05 times 10-9/L). Clinical symptoms were relevant, but their course was not fulminant; the two patients responded to different therapies (plasma or plasma plus plasmapheresis, and steroids), showing rapid improvement in symptoms. One patient remained asymptomatic with zidovudine only, while the other relapsed (probably due to an intercurrent infection). This second person is now asymptomatic on zidovudine plus low doses of steroids.