Serum selenium in patients with epidermoid carcinoma of the oral cavity and pleomorphic adenoma of the salivary glands
Jović, N.; Petrović, D.
Srpski Arhiv Za Celokupno Lekarstvo 122(5-6): 130-132
1994
ISSN/ISBN: 0370-8179 PMID: 17977407 Document Number: 422935
In 23 patients with epidermoid carcinoma of the oral cavity and in 13 patients with pleomorphic adenoma of the salivary gland blood selenium level was studied with hydride atomic absorptive spectrophotometry. Serum selenium was significantly lower in patients with epidermoid carcinoma of the oral cavity (79.37% lower than control values). In patients with pleomorphic adenoma of the salivary gland values were lower by 32.20% than control values. The results suggest the need of further epidemiological studies in order to determine the selenium concentration in the ground and the food. In this way the optimal dose of selenium for prevention of benignant and malignant diseases in the maxillofacial region, can be established.