Menstrual migraine, old and new
Guaschino, S.; Spinillo, A.; Sances, G.; Martignoni, E.
Clinical and Experimental Obstetrics and Gynecology 12(3-4): 67-71
1985
ISSN/ISBN: 0390-6663 PMID: 2933189 Document Number: 421712
The authors reviewed the connection between sex hormones and migraine crisis. Besides other exogenous factors, the fall in estradiol blood levels during the late luteal and premenstrual phase seems a causal factor in the origin of menstrual-related headaches. The behavior of migraine crisis during the various events of the female reproductive period support this view. The role of prolactin, follicle stimulating hormone, testosterone, and luteinizing hormone were also discussed. At the same time, menstrual migraine represents a model that fits perfectly with a neuroendocrine hypothesis which is based on a faulty chronobiological response of the so-called antinociceptive system.