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Lung injury by furanoterpenoids isolated from Fusarium solani infected sweet potato, Ipomea batatas

Parasakthy, K.; Shanthi, S.; Devaraj, S.N.

Indian Journal of Experimental Biology 31(4): 397-398

1993

ISSN/ISBN: 0019-5189
PMID: 8359843
Document Number: 420272
Intraperitoneal administration (1 mg/kg body/wt./day for 21 days) of crude extract of furanoterpenoids, isolated from F. solani damaged I. batatas caused pulmonary oedema in albino rats. The elevated broncho alveolar lavage (BAL) angiotensin converting enzyme (ACE), lactate dehydrogenase (LDH) and protein levels indicated lung damage. The estimation of pulmonary extracellular surfactant phospholipids showed an alteration in various phospholipid fractions.

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