Phagocytosis: problems and prospects
Maianskiĭ, A.N.
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 4: 52-55
1993
ISSN/ISBN: 0869-6047 PMID: 7687488 Document Number: 418055
The paper reviews the current status of the teaching of phagocytosis and its main trends of development, by making comments on the investigations of the receptor-dependent responses of phagocytes, their interaction with the endothelium, ways of realization of the effector potential of the phagosystem. It underlines an active role of phagocytes in general and partial pathology. A great emphasis is laid on the problem of cell conditioning (priming, deactivation) and its value in characterizing inflammatory complications and responses of the body. The physiological (homeostatic) and pathophysiological (pathogenic) activities of phagocytes are considered to be a reflection of the fundamental dialectics of the mechanisms determining stabilization and destabilization of homeostasis.