The glycolipid composition of Francisella tularensis strains with different degrees of attenuation
Sukhar', V.V.
Mikrobiolohichnyi Zhurnal 55(1): 8-12
1993
ISSN/ISBN: 0201-8462 PMID: 8446062 Document Number: 415021
The glycolipid composition of F. tularensis strains was investigated by silica gel thin-layer chromatography. Vaccine strains in contrast to virulent ones lacked glycolipid 8, possessed new glycolipid 8-a and a higher level of glycolipid 7. Low immunogenic strains had a decreased content of glycolipids, while avirulent non-immunogenic strain (15-a) nearly completely lost them. Thus, the glycolipid composition is associated with the level of attenuation, virulence and immunogenicity of F. tularensis.