The preventive activity of monoclonal antibodies specific to the lipopolysaccharide of Francisella tularensis

Khlebnikov, V.S.; Vetchinin, S.S.; Grechko, G.K.; Averina, A.A.; Golovlev, I.R.; Averin, S.F.; Zhemchugov, V.E.; Konovalov, S.I.; Anisimov, G.A.; Afanas'ev, S.S.; Khlebnikov, V.S; Vetchinin, S.S; Grechko, G.K; Averina, A.A; Golovlev, I.R; Averin, S.F; Zhemchugov, V.E; Konovalov, S.I; Anisimov, G.A; Afanas&apo; ev, S.S

Home

>

Node

>

Subnode

The preventive activity of monoclonal antibodies specific to the lipopolysaccharide of Francisella tularensis

Khlebnikov, V.S.; Vetchinin, S.S.; Grechko, G.K.; Averina, A.A.; Golovlev, I.R.; Averin, S.F.; Zhemchugov, V.E.; Konovalov, S.I.; Anisimov, G.A.; Afanas'ev, S.S.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 1992(9-10): 67-70

1992

ISSN/ISBN: 0372-9311

PMID: 1481610

Document Number: 400495

The preventive activity of five monoclonal antibodies (McAb) in experimental tularemia was evaluated. McAb produced by hybridoma FB11-k (IgG2a), specific to F. tularensis lipopolysaccharide, prevented the death of mice and guinea pigs infected with F. tularensis virulent strain 503 of the holarctic subspecies.