A new model to test platelet adhesion under dynamic conditions. Application to the evaluation of a titanium nitride coating
Dion, I.; Baquey, C.; Havlik, P.; Monties, J.R.
International Journal of Artificial Organs 16(7): 545-550
1993
ISSN/ISBN: 0391-3988 PMID: 8370610 Document Number: 414206
In order to evaluate under dynamic circumstances the in vitro platelet adhesion induced by rigid materials such as ceramic coatings deposited on selected substrates, a new model simulating a tube has been designed. In vitro platelet adhesion was assessed with this new model: the material was titanium nitride (TiN) deposited on Ti6A14V (TA6V) titanium alloy by a physical vapor deposition (PVD) process. The results were compared to those obtained with complete titanium carbide (TiC) graphite tubes coated with TiN by a chemical vapor deposition (CVD) process. The difference observed (less than 25%) in favor of the new system, could be due to the better surface state of the construction materials of this system. In fact it is a systemic error. However TiN confirms its good performance as a blood-contacting biomaterial. (Int J Artif Organs 1993; 16: 545-50)