Effect of interaction of oestrogen, testosterone and thyroid hormones on the serum ceruloplasmin level in rats
Schreiber, V.; Pribyl, T.
Physiologia Bohemoslovaca 1977(2): 129-137
1977
ISSN/ISBN: 0369-9463 PMID: 140385 Document Number: 414
Male rats were given estradiol benzoate (1 mg as an aquaeous microcrystal suspension i.m. twice a week), testosterone isobutyrate (0.5 mg as an aquaeous microcrystal suspension i.m. once a week) and dried thyroid (Thyreoidin SPOFA, 0.2% in food), alone or variously combined. Estradiol raised adenohypophyseal weight, the binding capacity of the adenohypophyseal proteins for thyroxine and the serum ceruloplasmin level. Testosterone and Thyreoidin inhibited all 3 of these reactions, but when they were administered together there was no summation of their inhibitory action. The nature of the relationships between the 3 given proteosynthetic reactions is discussed.
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