Hepatic capillariasis: first case report in the Republic of Korea
Choe, G.; Lee, H.S.; Seo, J.K.; Chai, J.Y.; Lee, S.H.; Eom, K.S.; Chi, J.G.
American Journal of Tropical Medicine and Hygiene 48(5): 610-625
1993
ISSN/ISBN: 0002-9637 PMID: 8517480 Document Number: 411544
A case of massive hepatic infection by Capillaria hepatica in a 14-month-old girl who presented with the symptom triad of persistent fever, hepatomegaly, and leukocytosis with eosinophilia is reported. Twenty-five cases of human infection with this parasite, mostly in children, have been reported in the literature. This is the first case of hepatic capillariasis reported in the Republic of Korea. The diagnosis was made by needle biopsy of the liver. Scanning electron microscopic examination of the biopsy specimen was also performed. Albendazole treatment (10-20 mg/kg/day) was given for 20 days and followed with thiabendazole therapy (25 mg/kg/day) for 27 days. The patient developed liver disease-related IgA nephropathy during the therapy. Two years after initial admission the child's condition was stable although hepatomegaly was still prominent. The literature dealing with proven cases of infection with C. hepatica is briefly reviewed. From AS A case of massive hepatic infection by Capillaria hepatica in a 14-month-old girl who presented with the symptom triad of persistent fever, hepatomegaly, and leukocytosis with eosinophilia is reported. Twenty-five cases of human infection with this parasite, mostly in children, have been reported in the literature. This is the first case of hepatic capillariasis reported in the Republic of Korea. The diagnosis was made by needle biopsy of the liver. Scanning electron microscopic examination of the biopsy specimen was also performed. Albendazole treatment (10-20 mg/kg/day) was given for 20 days and followed with thiabendazole therapy (25 mg/kg/day) for 27 days. The patient developed liver disease-related IgA nephropathy during the therapy. Two years after initial admission the child's condition was stable although hepatomegaly was still prominent. The literature dealing with proven cases of infection with C. hepatica is briefly reviewed.