The value of nerve biopsy in the diagnosis of familial amyloidosis
Heim, S.; Ulrich, J.
Schweizerische Rundschau für Medizin Praxis 82(1): 25-27
1993
ISSN/ISBN: 1013-2058 PMID: 8380504 Document Number: 411196
Nerve biopsies are useful for the etiological diagnosis of certain polyneuropathies. One of them is familial amyloidotic polyneuropathy, which can be diagnosed and specified on the basis of a Kongo-red stain and immunohistochemical analysis of the amyloid deposited in the nerve. This possibility is illustrated by a case report. A review of the various clinical, morphological and genetic aspects of these diseases is given.