Anaphylactoid reaction with suramin

Thibault, A.; Figg, W.D.; Cooper, M.R.; Prindiville, S.A.; Sartor, A.O.; Headlee, D.J.; Myers, C.E.; Thibault, A; Figg, W.D; Cooper, M.R; Prindiville, S.A; Sartor, A.O; Headlee, D.J; Myers, C.E

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Anaphylactoid reaction with suramin

Thibault, A.; Figg, W.D.; Cooper, M.R.; Prindiville, S.A.; Sartor, A.O.; Headlee, D.J.; Myers, C.E.

PharmacoTherapy 13(6): 656-657

1993

ISSN/ISBN: 0277-0008

PMID: 8302692

Document Number: 409861

Suramin, a drug used to treat parasitic diseases, is currently being investigated as a treatment for metastatic prostate cancer. A 73-year-old man had an anaphylactoid reaction following the first dose of suramin. It was treated successfully with epinephrine, diphenhydramine, and hydrocortisone. Investigators should be aware of the possibility of such a reaction with parenteral administration of this drug.